Best PvE Weapons in Destiny 2

Why are we focusing on PvE weapons? Let’s get straight to the point: PvE is the cornerstone of the Destiny 2 experience. This is where you’ll immerse yourself in story missions, tackling challenging strikes, and diving deep into dungeons and raids. The weapons you choose are more than just tools; they’re game-changers that can either catapult you to victory or leave you struggling in the dust.

The goal of this article is crystal clear: to provide you with a definitive list of top-tier PvE weapons that will enhance your gameplay and prepare you for the unique challenges that D2 has to offer.

TABLE OF CONTENTS

Adapting to the Fluid Meta of Destiny 2

Hey, Guardians, let’s get real. Destiny 2’s meta is like quicksand—always shifting. You can bet the game’s dynamics have changed again. If you’re not updating your loadout, you’re setting yourself up for failure.

Why does the meta matter? Simple. It dictates which weapons will give you an edge in PvE. It’s not just about firepower; it’s about having the right tools for the current challenges. Trust me, you don’t want to be the one dragging the team down in a raid.

So, how do you stay ahead? Keep yourself updated. Patch notes are your friend, and articles like this are your roadmap.

Destiny 2 Best PvE Weapons Summary Table

Weapon

Type

Category

Key Perks/Features

How to Get

Why It Dominates

Osteo Striga

Submachine Gun

Kinetic

Tracks targets, poisons groups

Witch Queen campaign + Enclave (DLC)

Unmatched crowd control with poison AoE

Wish-Ender

Bow

Kinetic

Passive Anti-Barrier, wall vision

Shattered Throne quest (Forsaken)

Anti-Barrier and high burst damage

Malfeasance

Hand Cannon

Kinetic

Exploding shots, 20% damage buff (Catalyst)

“Darkness in the Light” quest (Forsaken)

Synergy with Witherhoard, poisoned target damage

Age-Old Bond

Auto Rifle

Kinetic

Repulsor Brace, Destabilizing Rounds

Last Wish Raid (Forsaken)

Void synergy for add-clear

Sunshot

Hand Cannon

Energy

Explosive Rounds, chain explosions

“Fury” mission (Red War)

Crowd control with AoE explosions

Riskrunner

Submachine Gun

Energy

Arc Conductor, Superconductor

“A Spark of Hope” quest

Near-invincibility vs Arc enemies

Zaouli’s Bane

Hand Cannon

Energy

Explosive Payload, Incandescent

King’s Fall Raid (Craftable)

Solar synergy, explosive AoE

Loaded Question

Fusion Rifle

Energy

Auto-Loading Holster, Controlled Burst

Nightfall drop (no DLC)

Excels in double-special builds

Forbearance

Grenade Launcher

Energy

Ambitious Assassin, Chain Reaction

Vow of the Disciple Raid (Craftable)

Top-tier add-clearing

Cold Comfort

Rocket Launcher

Heavy

Envious Assassin, Bait and Switch

Ghosts of the Deep dungeon

Best-in-slot for burst DPS

Cataclysmic

Linear Fusion Rifle

Heavy

Fourth Time’s the Charm, Bait and Switch

Vow of the Disciple Raid (Craftable)

35% damage buff for precision hits

Gjallarhorn

Rocket Launcher

Heavy

Pack Hunter, extra rocket (Catalyst)

“And Out Fly the Wolves” quest (30th Anniversary)

Buffs ally rockets

Commemoration

Machine Gun

Heavy

Reconstruction, Killing Tally

Deep Stone Crypt Raid (Craftable)

Best 450 RPM for add-clear

Leviathan’s Breath

Bow

Heavy

High damage, utility

Exotic Kiosk (Shadowkeep)

Easy-to-use high-damage bow

Two-Tailed Fox

Rocket Launcher

Heavy

Applies 3 debuffs (Catalyst)

Exotic Engrams (no DLC)

Multi-debuff utility

Conditional Finality

Shotgun

Special Mention

Ignition synergy, one-shot champions

Root of Nightmares final boss (Lightfall)

Highest damage exotic shotgun

The Navigator

Trace Rifle

Special Mention

Woven Mail, grapple points

Ghosts of the Deep dungeon

Strand build support, survivability

Witherhoard

Grenade Launcher

Special Mention

AoE damage, synergy

Exotic Kiosk (no DLC)

Easy AoE and weapon synergy

Acasia’s Dejection

Trace Rifle

Special Mention

Target Lock, Incandescent

Root of Nightmares Raid

Best Solar Trace Rifle

Wilderflight

Grenade Launcher

Special Mention

Repulsor Brace, Vorpal Weapon

Spire of the Watcher dungeon

High DPS grenade launcher

Izanagi’s Burden

Sniper Rifle

Special Mention

Sniper + rocket synergy

Exotic Kiosk (no DLC)

High burst damage synergy

Arbalest

Linear Fusion Rifle

Special Mention

Compounding Force, Genesis (Catalyst)

Exotic Engrams/Xûr

Shield-piercing for all content

Rufus’s Fury

Auto Rifle

Primary Highlight

Reconstruction, Target Lock

Root of Nightmares Raid (Adept)

High mag size, damage perks

Quicksilver Storm

Auto Rifle

Primary Highlight

Grenade launcher mode

Lightfall DLC bonus

Huge AoE in alternate mode

Kinetic Weapons - The Must-Haves for PvE in Destiny 2

In Destiny 2’s PvE, Kinetic Weapons often play second fiddle to their flashier Energy and Heavy counterparts. But underestimate them at your peril. These workhorse weapons are the backbone of any well-rounded loadout, offering a blend of versatility, power, and ammo efficiency that can’t be ignored.

Osteo Striga: The Add-Clearing Machine

  • Why It Dominates: Poison damage + ease of use = unmatched crowd control.
  • Strengths:
    • Tracks targets and poisons groups
    • Great for clearing adds and damaging majors
  • How to Get: Complete The Witch Queen campaign and shape at the Enclave (requires DLC).

Wish-Ender: The Barrier Champion Slayer

  • Why It Dominates: Anti-Barrier and high burst damage in one.
  • Strengths:
    • Passive Anti-Barrier Champion mod
    • Sees through walls while drawn
  • How to Get: Quest in Shattered Throne dungeon (Forsaken).

Malfeasance

  • Why It Dominates: Exploding shots and bonus damage to poisoned targets.
  • Strengths:
    • Synergizes with Witherhoard
    • 20% damage buff with catalyst (Vorpal Weapon)
  • How to Get: “Darkness in the Light” questline (Forsaken).

Age-Old Bond

  • Why It Dominates: Void synergy with Repulsor Brace and Destabilizing Rounds.
  • How to Get: Last Wish Raid (Forsaken).

Energy Weapons - The Unsung Heroes of Destiny 2's PvE

In Destiny 2, especially in the Season of the Witch, your Energy Weapons can make or break your PvE experience. These weapons often provide the utility to deal with various enemy types and situations. Let’s dive into some of the top picks in this category.

Sunshot: The Crowd Control Maestro

Strengths:

  • Explosive Rounds: Deal area damage, excellent for crowd control.
  • High Fire Rate: Allows for quick successive shots.
  • Why It Dominates: Chain reaction explosions wipe out enemy groups.
  • How to Get: Complete the “Fury” mission (Red War content).

Riskrunner: The Elemental Powerhouse

Strengths:

  • Arc Conductor: Increases damage and chains lightning when taking Arc damage.
  • Superconductor: Doubles the chaining capabilities when the Arc Conductor is active.
  • Why It Dominates: Arc Conductor makes you unkillable vs Arc enemies.
  • How to Get: “A Spark of Hope” quest.

Zaouli’s Bane

  • Why It Dominates: Solar wave-frame synergy + explosive perks.
  • Perks: Explosive Payload + Incandescent
  • How to Get: King’s Fall Raid (Craftable).

Loaded Question

  • Why It Dominates: Fusion rifle that excels in double-special builds.
  • Perks: Auto-Loading Holster + Controlled Burst
  • How to Get: Nightfall weapon drop (no DLC required).

Forbearance

  • Why It Dominates: Add-clearing god in any PvE content.
  • Perks: Ambitious Assassin + Chain Reaction
  • How to Get: Vow of the Disciple Raid (Craftable).

The Heavy Hitters: Unleashing the Best Heavy Weapons in Destiny 2 for PvE

When dealing massive damage in Destiny 2’s PvE, nothing beats the raw power of Heavy Weapons. You turn to these tools when you need to obliterate a boss or clear a room full of enemies in the blink of an eye. 

Cold Comfort

  • Why It Dominates: Best-in-slot for burst DPS in raids.
  • Perks: Envious Assassin + Bait and Switch
  • How to Get: Ghosts of the Deep dungeon.

Cataclysmic: The Linear Fusion Powerhouse

Strengths:

  • Fourth Time’s the Charm: Rewards precision hits with returned ammo.
  • Bait and Switch: Increases damage after a successful kill.
  • Why It Dominates: Precision LFR with a devastating 35% damage buff.
  • Perks: Fourth Time’s the Charm + Bait and Switch
  • How to Get: Vow of the Disciple Raid (Craftable).

Gjallarhorn: 

  • Why It Dominates: Rocket launcher buff machine.
  • Strengths:
    • Pack Hunter perk boosts ally rockets
    • Catalyst adds extra rocket
  • How to Get: “And Out Fly the Wolves” quest (30th Anniversary pack).
Gjallarhorn

Commemoration: The Crowd-Clearing Machine

  • Why It Dominates: Best 450 RPM Machine Gun for clearing content.
  • Perks: Reconstruction + Killing Tally
  • How to Get: Deep Stone Crypt Raid (Craftable).

Leviathan’s Breath

Strengths:

  • Pack Hunter: Boosts damage for non-exotic rocket launchers used by allies.
  • Wolfpack Rounds: Missiles split into tracking cluster missiles upon detonation.
  • Why It Dominates: Easy-to-use high-damage bow with utility.
  • How to Get: Exotic Kiosk (Shadowkeep required).

Two-Tailed Fox

  • Why It Dominates: Applies 3 debuffs post-Catalyst.
  • How to Get: Exotic Engrams (no DLC needed).

Special Mentions: The Underdogs You Shouldn't Ignore in Destiny 2 PvE

Regarding Destiny 2’s PvE, the meta often overshadows some hidden gems that deserve a spot in your loadout. While they may not be the first weapons you think of, they offer unique advantages that can make your PvE experience more efficient and enjoyable. 

Conditional Finality

  • Why It Dominates: The highest damage exotic shotgun in the game.
  • Strengths:
    • Ignition synergy with Solar builds
    • One-shot potential on many champions
  • How to Get: Final boss in Root of Nightmares Raid (Lightfall).

The Navigator

  • Why It Dominates: Support weapon for Strand builds and survivability.
  • Strengths:
    • Grants Woven Mail to allies
    • Can create grapple points
  • How to Get: Ghosts of the Deep dungeon.

Witherhoard

  • Why It Dominates: Easy AoE + synergizes with other weapons.
  • How to Get: Exotic Kiosk (no DLC required).

Acasia’s Dejection

  • Why It Dominates: Best Solar Trace Rifle.
  • Perks: Target Lock or Incandescent
  • How to Get: Root of Nightmares Raid.

Wilderflight

  • Why It Dominates: High DPS grenade launcher.
  • Perks: Repulsor Brace + Vorpal Weapon
  • How to Get: Spire of the Watcher dungeon.

Izanagi’s Burden

  • Why It Dominates: Sniper + rocket combo damage synergy.
  • How to Get: Exotic Kiosk (no DLC required).

Arbalest

  • Why It Dominates: Shield-piercing for all content types.
  • Perks: Compounding Force + Catalyst adds Genesis
  • How to Get: Exotic Engrams or Xûr rotation.

PLUS 🌟 Primary Weapon Highlights

Rufus’s Fury

  • Why It Dominates: Auto Rifle with high mag size and damage perks.
  • Perks: Reconstruction + Target Lock
  • How to Get: Root of Nightmares Raid (Adept version).

Quicksilver Storm

  • Why It Dominates: Converts to grenade launcher mode for huge AoE.
  • How to Get: Lightfall DLC bonus weapon.
The Final Verdict

🚀 Let LFCarry Handle the Grind for You

Alright, Guardians, we’ve dissected the ins and outs of Destiny 2’s PvE weaponry, from meta dominators to underrated gems. Whether you’re a Destiny 2 veteran or a bright-eyed Kinderguardian, the right weapon can make or break your PvE experience. But let’s be real—sometimes, even the most god-rolled weapon isn’t enough to conquer the toughest challenges.

Don’t have time to farm Root of Nightmares 20 times? Still chasing a Cold Comfort god roll? LFCarry has your back.

  • Guaranteed weapon drops
  • Custom PvE builds
  • GM Nightfall clears and weekly rotations
  • Flexible scheduling with pro players

Start your PvE journey the efficient way with LFCarry →

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12 comments

  1. Plaguebringer77
    February 26, 2025 at 2:11 pm

    Solid list! Been running Witherhoard for ages, and it still slaps in PvE. Curious, though—do you think it’ll ever get a nerf?

  2. Grinder
    February 26, 2025 at 2:11 pm

    Love that you included underdog weapons. People always sleep on stuff like Graviton Lance, but it actually shreds in certain situations!

  3. Quickshot93
    February 26, 2025 at 2:12 pm

    Man, I really wish we’d get more love for sidearms in PvE. I know they’re more of a PvP thing, but they can be fun in the right setup.

  4. Tony Jankovic
    February 26, 2025 at 2:12 pm

    Gjallarhorn still dominating the Heavy slot after all these years. Some things never change. 😂

  5. Jerry
    February 26, 2025 at 2:13 pm

    Do you think Adaptive Frame pulse rifles are worth running in PvE now? Feels like they lack the punch compared to SMGs and hand cannons.

  6. IronLordDelta
    February 26, 2025 at 2:13 pm

    Kinetic weapons are in a weird place right now. Feels like if you’re not running Arbalest or a crafted Outlaw/Rampage hand cannon, you’re missing out.

  7. ArcTitanX
    February 26, 2025 at 2:13 pm

    Would love to see a follow-up article on best loadouts instead of just weapons. Synergy is everything in high-end PvE.

  8. Chillz89
    February 26, 2025 at 2:14 pm

    Glad to see you mention Coldheart. The sustained DPS it pumps out in PvE is seriously underrated!

  9. SolarBoi99
    February 26, 2025 at 2:14 pm

    Energy slot is stacked right now. Between Doom of Chelchis, Riptide, and BXR, I never know what to run!

  10. VexMythicMain
    February 26, 2025 at 2:14 pm

    Question: Is there a solid primary weapon that pairs well with Divinity? My team runs it a lot in raids, and I wanna maximize damage.

  11. RaidRaider
    February 26, 2025 at 2:15 pm

    Heavy weapons meta is wild. One season it’s rockets, next it’s linears, then it’s machine guns. Bungie really keeping us on our toes.

  12. SniperWolfXL
    February 26, 2025 at 2:15 pm

    I swear, if one more person tells me to use Izanagi’s Burden, I’m gonna lose it. 😂 It’s good, but I’m so tired of seeing it in every guide.

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